The founder, CIO, and CEO of Granite Point Capital, Warren Lammert, is a financial professional and portfolio manager who launched his financial career in 1984 as a research associate with Fred Alger Management in New York City. Leveraging his entrepreneurial experience, Warren B Lammert co-founded Tevard Biosciences, a company that studies gene therapies for Dravet syndrome and other rare genetic diseases.
While not all gene mutations result in disease, some debilitating diseases have been linked to a genetic mutation. A mutation is an abnormal alteration in the genetic makeup of an organism. Genes are expressed in cells when the specific arrangement of nucleotide bases (called codons) results in a definite sequence of amino acids, which results in a secondary protein structure.
Proteins carry out the function of the gene. In the case of mutation, the genetic sequence has changed, and the resulting protein may be different from what's supposed to be expressed. This change can be inconsequential, positive, or negative. If the change is negative, a genetic disease arises.
There are multiple debilitating diseases with subtypes that occur due to genetic mutations. Typical examples are cystic fibrosis, spinal muscular atrophy, and Duchenne muscular dystrophy. Cancers and certain metabolic disorders are also consequences of genetic mutations.
